Top 15 medical billing software solutions you should use in 2025

15 min read
April 29, 2025

In healthcare, billing shouldn’t be your biggest headache.

But for too many healthcare providers, billing errors, rejected claims, and slow payments pile up fast – and fixing them wastes time, money, and patience.

The good news? You don’t have to settle for software that makes it worse. 

With the right software, you can clean up your workflow, speed up payments, and finally get billing off your worry list.

In this guide, we’ll break down 15 of the best medical billing software options out there right now so you can make the best choice for your practice.

Let’s dive in!

EZClaim

EZClaim is a medical billing and scheduling software built to help small to mid-sized healthcare practices simplify the business side of their operations. 

It’s designed with flexibility in mind, offering both cloud-based and desktop options depending on what suits your practice best.

EZClaim

It’s especially useful for independent providers who want a reliable and affordable tool without a big IT department to run it.

Important features

  • Flexible deployment options

You can use EZClaim on the cloud or install it locally, whichever fits your needs better.

  • Insurance eligibility verification

You can check patients’ coverage before services are rendered to avoid denials.

  • Claim scrubbing tools

Identify and fix errors in claims before submitting them to payers to reduce rejections.

  • HIPAA-compliant security standards

EZClaim is fully HIPAA-compliant, so your patient data is safe.

EZClaim pros and cons

Pros


  • Affordable
  • Short learning curve
  • Integration options

Cons


  • Outdated interface
  • Limited features for larger providers

Pricing

According to Capterra, EZClaim’s pricing starts at $149 per user/month.

You can also directly buy their software license as a one-time purchase.

AllegianceMD

AllegianceMD is an all-in-one medical billing, EHR, and practice management software built specifically for small and medium-sized practices. 

What sets it apart is its strong focus on automation – it handles a lot of the heavy lifting behind the scenes so you can spend more time on patient care and less on paperwork.

AllegianceMD

It’s also a cloud-based solution, meaning you don’t have to worry about servers, installations, or maintenance.

Important features

  • Fully integrated EHR and practice management

You can run both the clinical and billing sides of your practice from one platform.

  • Automated billing and claims management

With AllegianceMD, you can submit claims automatically and track payments with minimal manual input.

  • AI-powered decision support tools

AllegianceMD comes with AI-powered decision support tools, so you can get smart suggestions to improve care and billing accuracy.

  • Built-in patient portal

With their patient portal, patients can book visits, pay bills, and message providers online.

AllegianceMD pros and cons

Pros


  • Strong automation features
  • Easy to use
  • Regular updates

Cons


  • More expensive
  • Occasional data delays

Pricing

According to Capterra, AllegianceMD starts at $349 per user/month.

PracticeSuite

PracticeSuite is a cloud-based medical billing, EHR, and practice management solution designed for growing healthcare practices. 

It’s known for offering a lot of flexibility – you can pick and choose the features you need instead of paying for a giant package.

PracticeSuite

It’s a smart choice if you’re looking for an affordable, customizable, and scalable billing solution.

Important features

  • Complete revenue cycle management

You can manage insurance claims, patient billing, and collections in one streamlined platform.

  • Flexible modular system

With PracticeSuite, you choose only the billing, EHR, scheduling, or reporting features your practice needs.

  • Customizable reporting and analytics

You can track revenue, denials, and operational performance with easy-to-read reports.

  • Mobile-friendly platform

You can access billing, scheduling, and patient records from any device.

PracticeSuite pros and cons

Pros


  • Flexibility
  • Scalability
  • Good value for smaller providers

Cons


  • Dated interface
  • Configuration time

Pricing

Because it’s modular and you can pick and choose which individual solutions you want, PracticeSuite doesn’t have one-size-fits-all pricing.

You can contact them for more information here.

AdvancedMD

AdvancedMD is a robust cloud-based platform offering medical billing, EHR, and practice management tools all under one roof.

It’s best suited for mid-sized to larger practices that need more advanced functionality and a high level of configurability.

AdvancedMD

Its strength lies in helping practices automate, organize, and optimize every part of their workflow – clinical, financial, and administrative.

Important features

  • Complete revenue cycle management

Automates the entire billing cycle, from insurance verification to final collections.

  • Customizable workflows and templates

You can adapt the software to fit your practice’s exact needs instead of changing how you work.

  • Business intelligence and analytics

Offers powerful data tools to help you track KPIs like revenue per visit and average reimbursement time

  • Fully integrated EHR and telemedicine solutions

With AdvancedMD, you can seamlessly connect patient care with billing and scheduling in one system.

AdvancedMD pros and cons

Pros


  • Highly customizable
  • Strong reporting capabilities
  • Scalability

Cons


  • Steep learning curve
  • Long setup time

Pricing

AdvancedMD doesn’t publicly disclose their pricing, you can contact them for a quote here.

CureMD

CureMD is an all-in-one cloud-based medical billing, EHR, and practice management solution designed to make healthcare administration easier for practices of all sizes.

CureMD.

It’s particularly well-known for its specialty-specific templates and flexible customization options, helping practices tailor workflows to their needs without unnecessary complexity.

Important features

  • Cloud-based medical billing

You can access billing tools securely from anywhere without installing heavy software.

  • Specialty-specific templates

CureMD saves time and improves accuracy with templates customized for different medical fields.

  • Real-time insurance verification

You can catch errors early and confirm patient coverage before providing services.

  • Integrated EHR and practice management

CureMD lets you manage patient care, scheduling, and billing all in one place.

CureMD pros and cons 

Pros


  • Highly customizable
  • Easy to use (after setup)
  • Full suite of tools

Cons


  • Long initial setup
  • Slow customer support

Pricing

CureMD doesn’t publicly disclose their pricing, you can contact them for a quote here.

CareCloud

CareCloud is a modern, cloud-based medical billing and practice management platform.

It stands out with its clean user interface, strong focus on patient experience, and flexible tools that help you boost efficiency without losing the personal touch.

CareCloud

It’s a great choice for practices that want scalable solutions without unnecessary complexity.

Important features

  • Denial prevention tools

CareCloud spots billing errors and coding issues before claims go out, helping you fix mistakes early and keep your revenue targets on track.

  • Intuitive interface

CareCloud has a modern, user-friendly interface which reduces staff training time.

  • Built-in patient engagement tools

You can send appointment reminders, collect feedback, and manage payments straight from CareCloud

  • Customizable workflows

You can easily adapt billing processes and patient communications to your practice’s needs.

CareCloud pros and cons

Pros


  • Modern interface
  • Strong reporting features
  • Patient engagement features

Cons


  • Complex onboarding
  • Occasional slowdowns

Pricing

CareCloud doesn’t publicly disclose their pricing, but you can contact them for more information here.

Athenahealth

Athenahealth is a cloud-based medical billing and practice management platform designed to simplify healthcare administration for practices of all sizes.

It’s especially known for its strong billing automation, large payer network, and hands-on support services that help maximize collections and speed up reimbursements.

Athenahealth

It’s a good choice if you want billing to feel like less of a daily headache.

Important features

  • Full-service revenue cycle management

You can get help managing claims, rejections, and appeals with Athenahealth’s billing experts.

  • Large, U.S.-wide payer network

Athenahealth is connected with top healthcare payers, which speeds up claims processing and minimizes denials.

  • Real-time analytics

You can monitor billing health, productivity, and revenue with easy-to-read insights.

  • Integrated EHR and patient management

With Athenahealth, you can centralize clinical and financial workflows to keep your operations running smoothly.

Athenahealth pros and cons

Pros: Strong automation tools, good customer support, intuitive and easy to use

Cons: Takes time to fully configure, users report higher costs

Pros


  • Strong automation tools
  • Good customer support
  • Intuitive and easy to use

Cons


  • Long configuration time
  • Users report higher costs

Pricing

Athenahealth’s pricing depends on your specific needs, so you’ll need to contact them for a specific quote.

DrChrono

DrChrono is a flexible, cloud-based medical billing, EHR, and practice management platform tailored for small to mid-sized practices.

It’s one of the more mobile-friendly solutions on the market, offering a highly customizable experience that works just as well on iPads and smartphones as on desktops.

DrChrono

DrChrono is a great fit if you need flexibility, modern tools, and strong billing features without feeling locked into rigid systems.

Important features

  • Mobile-first design

DrChrono is optimized for mobile phones and tablets, so you can easily access patient records, billing data, and schedules right from your device.

  • End-to-end billing management

They offer end-to-end billing management services, so you can fully focus on your patient care.

  • Customizable billing templates

You can tailor documentation and billing processes to your specific workflows.

  • Automated reminders for billing

You can cut down on no-shows and overdue balances with automated communication tools.

DrChrono pros and cons

Pros


  • Mobile-first
  • Highly customizable
  • Built-in telehealth features

Cons


  • Less polished
  • Occasional syncing issues

Pricing

DrChrono doesn’t publicly disclose their pricing, but they offer several different plans and you can request their pricing here.

Medisoft

Medisoft is a long-standing medical billing and practice management software used by small to mid-sized practices for decades.

Known for its affordability and reliability, it offers powerful billing tools in a package that doesn’t overwhelm users with unnecessary complexity.

Medisoft

It’s a solid choice for healthcare providers who want a practical, proven solution without paying for extra bells and whistles.

Important features

  • Easy to use desktop software

You can keep everything running locally if you prefer an on-premise solution over the cloud.

  • Payment processing integration

You can accept and process patient payments directly within the platform.

  • Robust billing and claims management

Medisoft has tools built to maximize reimbursements you can use to create, submit, and track insurance claims easily.

  • Eligibility verification

With Medisoft, you can confirm insurance coverage before services are provided to avoid payment delays.

Medisoft pros and cons

Pros


  • Reliability
  • Simple to learn
  • Affordable

Cons


  • Very dated user interface
  • Limited scalability

Pricing

Medisoft offers several pricing options with a one-time payment for a license, ranging from $629 to $4,579.

Medisoft pricing

They also offer a cloud-based option, priced at $69 per user/month.

CollaborateMD

CollaborateMD is a cloud-based medical billing and practice management solution built for speed and simplicity.

It’s especially popular among smaller practices and billing services that want fast claims processing, easy-to-learn tools, and strong customer support.

CollaborateMD

It focuses on helping practices get paid faster without overcomplicating billing workflows.

Important features

  • Fast claim submission and real-time tracking

With CollaborateMD, you can submit insurance claims quickly and track their status at every stage.

  • Intuitive, user-friendly interface

Comes with an easy to use, intuitive interface so you can get new staff up and running with minimal training time.

  • Integration with EHR platforms

CollaborateMD can easily integrate with top EHR platforms, so you can seamlessly connect billing to clinical workflows for smoother operations.

  • Customizable reporting dashboards

You can monitor revenue, outstanding claims, and collections with easy-to-read visuals.

CollaborateMD pros and cons

Pros


  • Fast claims processing
  • Easy to use
  • Highly rated customer support

Cons


  • Limited advanced features
  • No built-in EHR

Pricing

CollaborateMD’s pricing starts at $225 per provider/month for their starter plan.

They don’t disclose pricing for their other tiers, you’ll have to get a custom quote here.

Billiyo

Billiyo is an all-in-one billing, business management, and compliance platform designed specifically for home healthcare agencies, therapy providers, and non-emergency medical transportation companies.

Billiyo

It combines billing, scheduling, documentation, and compliance into a single cloud-based platform built to meet the unique needs of these industries.

Important features

  • End-to-end revenue cycle management

You can automate claims submission, tracking, and collections to speed up cash flow.

  • Specialized tools for home healthcare and therapy

Billiyo offers specialized tools designed for agencies, not just general medical practices.

  • Mobile-friendly design for field staff

Caregivers and therapists can easily access and update records from their mobile devices.

  • HIPAA-compliant, cloud-based platform

Billiyo has strict security standards to protect sensitive patient data and billing information.

Billiyo pros and cons

Pros


  • Strong compliance features
  • Easy to use
  • Smooth integration

Cons


  • Complex setup
  • Not the best fit for traditional practices

Pricing

Billiyo’s pricing isn’t public, but you can contact them for a quote here.

Tebra

Tebra is a new, unified platform formed by the merger of Kareo and PatientPop, offering medical billing, practice management, and marketing solutions all in one place. 

Tebra

It’s built for modern practices that want to combine billing efficiency with patient acquisition and engagement tools.

This way, you grow your business while also getting paid faster.

Important features

  • Comprehensive billing and revenue cycle management

With Tebra, you can manage billing, claims, and payments in one streamlined, easy to use system.

  • Practice growth and marketing tools

Tebra lets you easily build your online presence, manage reviews, and attract new patients.

  • Automated eligibility checks

You can reduce claim denials and speed up reimbursement with their built-in verification tools.

  • Detailed financial and operational reporting

You can track revenue, patient acquisition, and operational efficiency through customizable dashboards.

Tebra pros and cons

Pros: Strong automation features, clean interface, comprehensive set of tools

Cons: Steeper learning curve, expensive with all features

Pros


  • Strong automation features
  • Clean interface
  • Comprehensive set of tools

Cons


  • Steep learning curve
  • Expensive with all features

Pricing

Tebra offers a wide range of tools you can use, so there’s no uniform pricing – contact them for a tailored quote here.

Claimocity

Claimocity is a medical billing platform built specifically for busy physicians, particularly those working in hospitals, urgent care centers, and concierge practices. 

Claimocity

It focuses heavily on speed, automation, and reducing administrative workload, making it a great fit for providers who want to spend less time billing and more time with patients.

Important features

  • Automated charge capture

You can quickly capture charges at the point of care and send claims instantly.

  • AI-powered task automation

Claimocity reduces manual data entry and repetitive administrative tasks through smart automation.

  • Dedicated billing service support

Claimocity offers access to a team of billing experts for help with complex claims and appeals.

  • Advanced analytics

You can easily monitor billing efficiency, revenue cycle timelines, and claim rejection rates.

Claimocity pros and cons

Pros: Fast, mobile-first design, automation features, strong customer support

Cons: Lacks fully customizable reporting, pricey premium features

Pros


  • Fast
  • Mobile-first design
  • Automation features

Cons


  • No fully customizable reporting
  • Niche focus

Pricing

Claimocity’s pricing isn’t public, you can contact them for an estimate here.

RXNT

RXNT is a cloud-based medical billing, EHR, and practice management solution designed for small to mid-sized healthcare practices. 

RXNT

It offers a full suite of healthcare software at an affordable price, helping you stay organized, compliant, and financially healthy without overwhelming your team.

Important features

  • Integrated billing, EHR, and practice management system

RXNT centralizes clinical, financial, and administrative tasks into one easy-to-use platform.

  • Automated claims management and submission

With RXNT, you can handle insurance claims from creation to reimbursement more efficiently, cutting down on manual work.

  • Patient portal with billing and communication tools

RXNT gives patients an easy way to pay bills, manage appointments, and message providers.

  • Integrated claims clearinghouse

You can submit claims directly through RXNT’s built-in clearinghouse without needing third-party services.

RXNT pros and cons

Pros: Easy setup, affordable, strong customer support

Cons: Limited advanced customization, occasional system glitches

Pros


  • Easy setup
  • Affordable
  • Strong customer support

Cons


  • Limited advanced customization
  • Occasional system glitches

Pricing

RXNT’s practice management bundle, which includes medical billing, is $207 per provider/month while their EHR comes in at $118 per provider/month.

RXNT pricing

You can also get their full suite of products for $319 per provider/month, billed annually.

ModMed

ModMed is a specialty-specific, cloud-based EHR and billing platform designed to meet the unique needs of dermatology, ophthalmology, orthopedics, and other specialty practices. 

ModMed

It’s built to simplify clinical documentation and billing with powerful automation and specialty-specific workflows.

Important features

  • Specialty-specific EHR and billing modules

You can use workflows, templates, and billing codes tailored for your specialty right out of the box.

  • Patient engagement tools

ModMed offers online scheduling, intake forms, reminders, and bill payment through a secure portal.

  • Built-in revenue cycle management services

ModMed helps handle claims, denials, and collections with expert billing support if needed.

  • Telehealth platform fully integrated with billing

The platform supports virtual patient visits and it’s fully integrated, so you can bill for them without switching systems.

ModMed pros and cons

Pros: Specialty-specific features, highly customizable, integrated telehealth

Cons: Initial learning curve, limited report customization

Pros


  • Specialty-specific features
  • Highly customizable
  • Integrated telehealth features

Cons


  • Initial learning curve
  • Limited report customization

Pricing

ModMed’s pricing isn’t public, you’ll have to contact them for a quote here.

Medical billing software: FAQs

Start by figuring out your specialty needs and whether you want an all-in-one solution or just billing features. 

Budget, ease of use, and customer support are just as important as features.

And remember, pricing most often depends on the size of your practice – so an all-in-one solution could better suit your needs if you’re on a budget.

For most practices, yes.

Cloud-based tools give you:

  • More flexibility
  • Automatic updates
  • Better security

And you get all of this without needing in-house IT support. But some smaller clinics still prefer a desktop setup for simplicity.

Most modern billing platforms are either part of a larger software solution that includes EHRs or offer strong integration options with the top EHRs on the market.

But, you should always double-check before you buy.

Not satisfied with your medical billing software?

Have you tried some of these tools and they all missed the mark? Or you can’t find a tool that fully meets your needs?

Well, this means you likely need a custom healthcare software solution. And that’s where we come in.

We’re an EU-based, high-caliber software development company with 12+ years of experience delivering complex software solutions for some of the world’s biggest companies.

And we can help you build a full range of healthcare software solutions, everything from EHRs to medical billing software, tailored to your specific needs.

If you want to learn more, feel free to reach out and our team will be happy to discuss your needs in more detail.

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Written by

Marin Luetic

Chief Client Officer

A seasoned software engineering executive, Marin’s role combines his in-depth understanding of software engineering processes (particularly mobile) with product and business strategies. Humbly boasting 20+ years of international experience at the forefront of telecoms, Marin knows how to create and deliver state of the art software products to businesses of all sizes. Plus, his skills as a lifelong basketball player mean he can lead a team to victory. When he’s not hopping from meeting to meeting, you’ll find Marin listening to indie rock, or scouring the latest IT news.

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